Prognostic relevance of cellular morphology in multiple myeloma

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Prognostic relevance of cellular morphology in multiple myeloma.

Morphological characteristics of tumor cells have been employed in the prognosis of lymphomas and solid tumors. This report documents an attempt to predict survival from the known cytologic heterogeneity in multiple myeloma. Myeloma cells in bone marrow smears from patients at diagnosis were evaluated by assigning them to morphologically defined categories. Cox's multivariate regression model f...

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Introduction: Multiple myeloma is a heterogeneous disease with different survival times among patients. Accurate prediction of prognosis in multiple myeloma is essential, as patients with a shorter survival time may require early bone marrow transplantation (BMT) and more advanced chemotherapy as a part of their first-line treatment. In the present study, a parameter, depicted by ga...

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Prognostic factors in multiple myeloma.

All patients with multiple myeloma seen over a 9-year period at Tygerberg Hospital were studied retrospectively. Presentation data of 144 patients, as well as individual laboratory results were included in the survival analysis. Cox's proportional hazard model (a non-parametric multivariate regression method) was used to predict survival and divide patients into prognostic groups. The relations...

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A Tentative Staging of Multiple Myeloma by Utilizing Respective Coefficients of Prognostic Factors

Introduction: Multiple myeloma is a heterogeneous disease with different survival times among patients. Accurate prediction of prognosis in multiple myeloma is essential, as patients with a shorter survival time may require early bone marrow transplantation (BMT) and more advanced chemotherapy as a part of their first-line treatment. In the present study, a parameter, depicted by ga...

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ژورنال

عنوان ژورنال: Blood

سال: 1984

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v63.5.1072.1072